The chemical composition of plant oils is more complex with many more possible allergens or irritating components, while mineral oil is simple, pure and sensitivity to it is extremely rare. If you check out the classic French pharmacy brands and their moisturizers for the most sensitive, allergy prone skin, they usually contain mineral oil. The other thing that mineral oil is really good at is being non-irritating to the skin. When compared to heavy-duty plant oil, extra virgin coconut oil, the two of them were equally efficient and safe as moisturizers in treating xerosis, a skin condition connected to very dry skin. It is a great emollient and moisturizer working mainly by occlusivity. Occlusivity is one of the basic mechanisms of how moisturizers work and it means that mineral oil sits on top of the skin and hinders so-called trans-epidermal water loss, i.e water evaporating out of your skin. Chemically speaking, cosmetic grade mineral oil is a complex mixture of highly refined saturated hydrocarbons with C15-50 chain length. It is not merely a "by-product" but rather a specifically isolated part of petroleum that is very pure and inert. Trust us, if something is used for more than 100 years in cosmetic products, it has advantages. It is a very controversial ingredient with pros and cons and plenty of myths around it. The clear oily liquid that is the "cheap by-product" of refining crude oil and the one that gets a lot of heat for its poor provenance. This Israeli study was a randomized, controlled trial comparing SSD, biafine, and saline-soaked gauze in the treatment of inflicted superficial partial-thickness burns in pigs.The famous or maybe rather infamous mineral oil. Ufberg, Assistant Professor of Emergency Medicine, Assistant Residency Director, Department of Emergency Medicine, Temple University School of Medicine, Philadelphia, PA, is on the Editorial Board of Emergency Medicine Alert. Rates from the laboratory to the ED, but only a larger human study will give usĭr. It is much easier to extrapolate the results regarding wound-healing With saline-soaked gauze would have higher infection rates in a real-world There is no way to know from this small animal study whether patients treated One of the primary purposes of SSD and biafine is the theoretical ability to help prevent superinfection. In the ED, not all burns are of the same type or size, and some patients may be more prone to wound infections due to hygiene, wound care, co-morbidity, and other factors. These burns were inflicted by a standardized method using a heated aluminum bar in laboratory animals in a controlled setting. This is a very interesting study that is not yet ready for clinical application. No clinical wound infection was noted in any of the inflicted The treatment arm was not aĭetermining factor for the decrease in burn area afterĬontrolling for pig number and burn location. + 1.3 days in the SSD group, 13.5 + 0.9 days in theīiafine group, and 13.5 + 1.0 days in the saline-soaked gauze group. Complete wound healing was noted after 13.3 Time to complete re-epithelialization among the The primary outcome measure was the time to complete re-epithelialization of the burn, with secondary outcomes including the decrease in the open area of the wound and the incidence of clinical infection (defined as the presence of erythema, warmth, and/or purulence at the wound site).Ī total of 32 wounds were inflicted, with 12 randomized to the SSD arm, 12 to the biafine arm, and 8 to the Assessment of wound re-epithelialization was performed visually using a standardized method when the dressings were changed. Each burn was assigned randomly to one of the three treatment groups.Īn investigator cleaned the wounds with an antiseptic solution and saline and then re-dressed the wounds every other day. The necrotic epidermis was not debrided after the burn was induced. ![]() Eight standardized burns involving 30-50% of the dermal depth were inflicted on each of four pigs. The treatment of inflicted superficial partial-thicknessīurns in pigs. ![]() This Israeli study was a randomized, controlled trialĬomparing SSD, biafine, and saline-soaked gauze in No prior study had compared these treatments in the care of partial-thickness burns. It has been shown to increase the interleuken (IL)-1 to IL-6 ratio, and to be chemotactic for macrophages. Biafine is an emulsion-containing alginate that also has been used in the treatment of superficial partial-thickness burns. It has been shown to speed re-epithelialization, reduce bacterial contamination, and slow wound contracture. The most commonly used local treatment for burns is 1% silver sulfadiazine (SSD) cream. ![]() Randomized controlled trial of silver sulfadiazine, biafine, and saline-soaked gauze in the treatment of superficial partial-thickness burn wounds in pigs. Is Biafine an Alternative to Silver Sulfadizine for the Treatment of Burns?
0 Comments
Leave a Reply. |